William Howard Stein (1911 nî 6 goe̍h 25 ji̍t – 1980 nî 2 goe̍h 2 ji̍t) sī chi̍t ūi Bí-kok ê hòa-ha̍k-ka. I mā-sī 1972 nî Nobel Hòa-ha̍k Chióng ê ti̍t-chióng-jîn; i ti̍t-chióng ê lí-iû sī for their contribution to the understanding of the connection between chemical structure and catalytic activity of the active centre of the ribonuclease molecule.