Thó-lūn:Le̍k-sek êng-kng nn̄g-pe̍h-chit
(Tùi 綠色螢光卵白質 choán--lâi)
綠色螢光卵白質
siu-kái綠色螢光卵白質,英語 green fluorescent protein,簡寫GFP,是一款卵白質,有228个氨基酸,質量26.9kDa,GFP一開始是對學名Aequorea victoria的水母分離出來,這款水母佇藍色光線下跤會發綠色的螢光。[1][2]
製造GFP的基因會當做基因表達的報導基因 (reporter gene),[3] 佇現在的細胞生物學抑分子生物學的研究內底有真濟應用,2008年,Martin Chalfie、Osamu Shimomura佮Roger Y. Tsien因位對GFP的發現參研究,得著Nobel化學獎。
參考文獻
siu-kái- ↑ Prendergast F, Mann K (1978). "Chemical and physical properties of aequorin and the green fluorescent protein isolated from Aequorea forskålea". Biochemistry. 17 (17): 3448–53. doi:10.1021/bi00610a004. PMID 28749.
- ↑ Tsien R (1998). "The green fluorescent protein" (PDF). Annu Rev Biochem. 67: 509–44. doi:10.1146/annurev.biochem.67.1.509. PMID 9759496.
- ↑ Phillips G (2001). "Green fluorescent protein--a bright idea for the study of bacterial protein localization". FEMS Microbiol Lett. 204 (1): 9–18. doi:10.1016/S0378-1097(01)00358-5. PMID 11682170.